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Title: The Gene
Author: Siddhartha Mukherjee
Publisher Name: Vintage
Publication time: 2017
Language: English
ISBN: 9780099584575
Product size: 12.9 x 3.1 x 19.8 cm
Packing: paperback
Number of pages: 608
10 reasons to read The Gene:
1. Not all books about genes can be read by you, except for this one written by Mukherjee.
2. The story in this book is closely related to every living person. All your questions about pathology, behavior, personality, disease, race, identity, and destiny will find new answers in the book.
3. Who are you? Where did it come from? Where to go? The discovery of genes has finally brought us infinitely close to the true answers to these big questions.
4. This book has written human beings' exploration of the mystery of life genetic iteration for 3000 years.
5. Why are everyone similar but so different? In the evolution of life, what is behind it that determines all of this? This problem has plagued mankind for thousands of years. From Aristotle to Darwin, mankind has always explored it. Until the 1950s, scientists found genes and finally found the key to the mystery of life.
6. Genes are not emotional, "Gene Biography" is warm. The whole book is about 240 scientists who have overcome difficulties in the process of exploring genetic mysteries.
7. There are a lot of books about genes before, but they are all scattered. There has never been a complete and systematic analysis of the origin, development and future of gene theory like Mukherjee. "Gene Biography" is a highly knowledge-density book. excellent work.
8. This is not a blunt popular science book. The author also intersperses issues such as politics, history, human nature, ethics, and morality into it. It is a thick work. This book can give us a complete understanding of all the knowledge of genes. Regarding genes, this is enough.
9. Indian-American doctor, such an identity, makes the author's writing unique. Mukherjee's previous work "The King of Diseases: A Biography of Cancer" won the Pulitzer Prize. He is a very good storyteller.
10. Mukherjee is handsome, eh!
Media comments:
"No one is better suited to lead us through the past, present, and future of genetic science... At the same time, Mukherjee is an elegant, storyteller."-Bill Gates
"Genetic Biography" not only depicts a magnificent blueprint for the development of life sciences, but also poses a moral and philosophical challenge to traditional human concepts."-Paul Berg (Nobel Laureate in Chemistry)
"This work, which is radical, yet controversial and affinity in the modern context, is so exciting. Read it and equip yourself for the coming of the future."
——Brian Aboya (author of "How to live forever"), "Sunday Times"
"His (Mukherjee) clarified and fascinating account of the (genetic) historical context is a manifestation of his ambition and a testimony of his indelible achievements. It is worth mentioning that none of his books are missing. A credible and vivid investigation."-"Guardian"
"This is a masterpiece that encompasses complex ideas... Chinese writing is meticulous, readable and interesting. It can be said to be one of the important works in all scientific revolutions. It is destined to produce for our next generation. Fundamental impact."
-"The Observer"
"Genesis" explores an eternal and complex theme. In fact, it is intertwined with our daily lives, and the author makes it closer to us and more exciting."-Mark Hayden ("Midnight Puppy" Author of "Mystery Exercises")
Selected as a Book of the Year by The New York Times, The Economist, Independent, Observer and Mail on Sunday
THE NEW YORK TIMES NUMBER ONE BESTSELLER
SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017
The Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee.
Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function.
This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.
The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856 where a monk stumbles on the idea of a ‘unit of heredity’. It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.
Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.
Review
"With a marriage of architectural precision and luscious narrative, an eye for both the paradoxical detail and the unsettling irony, and a genius for locating the emotional truths buried in chemical abstractions, Mukherjee leaves you feeling as though you’ve just aced a college course for which you’d been afraid to register ― and enjoyed every minute of it"
(Andrew Solomon Washington Post)
"[Siddhartha Mukherjee] is the perfect person to guide us through the past, present, and future of genome science… It is up to all of us―not just scientists, government officials, and people fortunate enough to lead foundations―to think hard about these new technologies and how they should and should not be used. Reading The Gene will get you the point where you can actively engage in that debate."(Bill Gates Gatesnotes)
"The Gene is prodigious, sweeping, and ultimately transcendent. If you’re interested in what it means to be human, today and in the tomorrows to come, you must read this book."
(Anthony Doerr, Pulitzer Prize-winning author of All the Light We Cannot See)
"Dramatic and precise... [A] thrilling and comprehensive account of what seems certain to be the most radical, controversial and, to borrow from the subtitle, intimate science of our time... He is a natural storyteller... A page-turner... Read this book and steel yourself for what comes next." (Bryan Appleyard Sunday Times)
"The story […] has been told, piecemeal, in different ways, but never before with the scope and grandeur that Siddhartha Mukherjee brings to his new history, The Gene. He fully justifies the claim that it is “one of the most powerful and dangerous ideas in the history of science.” … Definitive"(James Gleick New York Times Book Review)
Throughout the 20th century, three subversive scientific concepts and technological applications led human society to a new historical stage: the discovery of "atoms" brought a revolution in physics, and the discovery of "bytes" brought a revolution in the Internet. The discovery of "gene" brought a revolution in biology.
Genes are not only the basic unit of genetic material, but also the basis of all biological information. Deciphering the operating mechanism of genes also deciphers the mystery of life. Human pathology, behavior, personality, disease, race, identity, and destiny are also updated. s answer. Nowadays, genetic technologies such as gene sequencing and gene cloning have developed rapidly. The Human Genome Project has also completed the comparison and sequencing of all human genes. The era of human conquest of genes has arrived.
The Gene "Gene Biography" is a rare and complete story about the origin, development and future of gene theory, unfolding in chronological order and storyline, it is a biography that reflects the history of gene development.
"Gene Biography" is also a story of scientists overcoming difficulties in the process of exploring the mysteries of genes. Like a detective novel, it uses new problems that scientists are constantly encountering as clues step by step, and it has combed the genetic theory in a profound and simple way. The context has truly recorded the cooperation and struggle, success and failure of scientists.
"Gene Biography" also tells about the historical disasters and lessons caused by political distortion and utilization of gene theory, as well as the collision and game between gene technology and system, culture, ethics, and morality. With wonderful stories, human entanglements, and historical advances and retreats, "Gene Biography" is a warm, superb narrative general reading material.
Human beings have never been so close to the truth of life as they are today. When we can control and modify human genes, the concept of "humanity" may fundamentally change, and the post-human era is coming. The story told by "Gene Biography" is closely related to everyone.
Siddhartha Mukherjee is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a staff cancer physician at the CU/NYU Presbytarian Hospital. A former Rhodes scholar, he graduated from Stanford University, University of Oxford (where he received a PhD studying cancer-causing viruses) and from Harvard Medical School. His work was nominated for Best American Science Writing, 2000 (edited by James Gleick). He lives in Boston and New York with his wife, Sarah Sze, an artist, and with his daughter, Leela.
The monastery was originally a nunnery. The monks of Saint Augustine’s Order had once lived—as they often liked to grouse—in more lavish circumstances in the ample rooms of a large stone abbey on the top of a hill in the heart of the medieval city of Brno (Brno in Czech, Brunn in German). The city had grown around them over four centuries, cascading down the slopes and then sprawling out over the flat landscape of farms and meadowlands below. But the friars had fallen out of favor with Emperor Joseph II in 1783. The midtown real estate was far too valuable to house them, the emperor had decreed bluntly—and the monks were packed off to a crumbling structure at the bottom of the hill in Old Brno, the ignominy of the relocation compounded by the fact that they had been assigned to live in quarters originally designed for women. The halls had the vague animal smell of damp mortar, and the grounds were overgrown with grass, bramble, and weeds. The only perk of this fourteenth century building—as cold as a meat house and as bare as a prison—was a rectangular garden with shade trees, stone steps, and a long alley, where the monks could walk and think in isolation.
The friars made the best of the new accommodations. A library was restored on the second floor. A study room was connected to it and outfitted with pine reading desks, a few lamps, and a growing collection of nearly ten thousand books, including the latest works of natural history, geology, and astronomy (the Augustinians, fortunately, saw no conflict between religion and most science; indeed, they embraced science as yet another testament of the workings of the divine order in the world). A wine cellar was carved out below, and a modest refectory vaulted above it. One-room cells, with the most rudimentary wooden furniture, housed the inhabitants on the second floor.
In October 1843, a young man from Silesia, the son of two peasants, joined the abbey. He was a short man with a serious face, myopic, and tending toward portliness. He professed little interest in the spiritual life— but was intellectually curious, good with his hands, and a natural gardener. The monastery provided him with a home, and a place to read and learn. He was ordained on August 6, 1847. His given name was Johann, but the friars changed it to Gregor Johann Mendel.
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